Discussion
As men pass through and beyond middle age, hormonal changes occur which can impact the prostate gland. Levels of dihydrotestoterone (DHT), a normal metabolite of testosterone, increase. This, plus an increased binding of DHT to nuclear receptors in the prostate cell, results in growth of prostate tissue. This tissue growth takes place in the part of the prostate which surrounds the urethra, the tube for urine excretion. This can constrict the urethra, resulting in urinary disturbances.
Saw palmetto extract has been shown to inhibit 5 alpha-reductase, an enzyme that controls conversion of testosterone to DHT. Saw palmetto extract also blocks the binding of DHT to prostate cells. These mechanisms are believed to account for Saw palmetto extract's positive effect on prostate gland structure.
In clinical studies, Saw palmetto extract has produced measurable improvements in urinary functions and prostate size. Quality of life scores have also improved.
The results with Saw palmetto extract have been duplicated in open trials and controlled, double-blind studies.
Saw palmetto extract is safe and virtually free of side-effects.
Saw palmettos effectiveness comes from its content of natural fatty acids and sterols. These include oleic acid, lauric acid, campasterol, stigmasterol, beta-sitosterol and others. The standard of quality for Saw palmetto extract products is a high concentration of fatty acids and sterols, equaling 90%
